Glutathione pills for skin whitening review

Glutathione is a low molecular weight thiol-tripeptide that plays a prominent role in maintaining intracellular redox balance. In addition to its remarkable antioxidant properties, the discovery of its antimelanogenic properties has led to its promotion as a skin-lightening agent. It is widely used for this indication in some ethnic populations. However, there is a dichotomy between evidence to support its efficacy and safety. The hype around its depigmentary properties may be a marketing gimmick of pharma-cosmeceutical companies. This review focuses on the various aspects of glutathione: its metabolism, mechanism of action and the scientific evidence to evaluate its efficacy as a systemic skin-lightening agent. Glutathione is present intracellularly in its reduced form and plays an important role in various physiological functions. Its skin-lightening effects result from direct as well as indirect inhibition of the tyrosinase enzyme and switching from eumelanin to phaeomelanin production. It is available in oral, parenteral and topical forms. Although the use of intravenous glutathione injections is popular, there is no evidence to prove its efficacy. In fact, the adverse effects caused by intravenous glutathione have led the Food and Drug Administration of Philippines to issue a public warning condemning its use for off-label indications such as skin lightening. Currently, there are three randomized controlled trials that support the skin-lightening effect and good safety profile of topical and oral glutathione. However, key questions such as the duration of treatment, longevity of skin-lightening effect and maintenance protocols remain unanswered. More randomized, double-blind, placebo-controlled trials with larger sample size, long-term follow-up and well-defined efficacy outcomes are warranted to establish the relevance of this molecule in disorders of hyperpigmentation and skin lightening.

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How long does it take for glutathione pills to lighten skin?

results visible on Light-medium brown skin: 1-3 months, Dark brown skin: 3-6 months, Very dark skin: 6-12 months & Black skin: 18 months minimum and above.

Which tablet is best for permanent skin whitening?

Overall, we highly recommend the KUR Live Simply Glutathione Whitening Pills for anyone looking for a safe and effective way to whiten their skin and achieve a more even-toned complexion.

What kind of glutathione is best for skin whitening?

Top 3 Best Glutathione Supplements for Skin Whitening.

Luma Nutrition Glutathione Supplement..

Natural Vore Glutathione Supplement..

VAITE Glutathione Whitening Pills..

Are glutathione pills worth it?

Glutathione is involved in tissue building and repair, making chemicals and proteins needed in the body, and in immune system function. People take glutathione for aging, alcohol use disorder, liver disease, heart disease, and many other conditions, but there is no good scientific evidence to support these uses.